This kit uses RT-PCR to detect human isocitrate dehydrogenase (IDH1 and IDH2) and FMS-like tyrosine kinase 3 (FLT3) gene mutations in plasma or formalin-fixed paraffin-embedded tissue (FFPE). Test results may serve as a reference for clinical evaluation of defined IDH1, IDH2 and FLT3 gene mutations in acute myeloid leukemia (AML) patients. Confirmed mutation: recommended medications include ivosidenib, enasidenib, gilteritinib, midostaurin
The test uses specific gene sequences as PCR target regions. Human genomic sequence is used as internal quality control.
